Gli family zinc finger 1
WebJan 1, 2024 · GLI1, the first of the GLI family characterized in humans, was identified in 1987 as a highly expressed gene in human glioma (Kinzler et al. 1987 ). Both GLI2 and GLI3 were discovered in 1988 through the use of cloned GLI1 cDNA as a probe targeting similar sequences (Ruppert et al. 1988 ). WebBackground and aims: The cluster of differentiation 47 (CD47)-signal regulatory protein alpha (SIRPα) signaling pathway plays important roles in immune homeostasis and tissue inflammatory response. Activation of the Hedgehog/smoothened (SMO)/GLI family zinc finger 1 (Gli1) pathway regulates cell growth, differentiation, and immune function.
Gli family zinc finger 1
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WebFeb 27, 2024 · GLI-1 (GLI family zinc finger 1), also known as Glioma-associated oncogene or oncogene GLI, is a 1,106 amino acid protein that localizes to both the cytoplasm and nucleus, and belongs to the GLI C2H2-type zinc-finger protein family. GLI-1 acts as a transcriptional activator and is thought to play a role in craniofacial development. WebJun 26, 2024 · The transcription factor GLI1 (GLI family zinc finger 1) plays a key role in the development and progression of multiple malignancies. To date, regulation of …
WebHuman GLI-1 Antibody Summary Species Reactivity Human Specificity Detects human GLI-1 in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human GLI-3 is … WebZDB-GENE-030321-1 Name GLI family zinc finger 1 Symbol gli1 Nomenclature History Previous Names. detour; dtr; Type protein_coding_gene Location Chr: 6 Mapping …
WebJul 26, 2011 · GLIS FAMILY ZINC FINGER PROTEIN 1; GLIS1 Alternative titles; symbols. GLI-SIMILAR PROTEIN 1 HGNC Approved Gene Symbol: GLIS1 ... A. M. Regulatory role for Kruppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis J. Invest. Derm. 126: 49-60, 2006. ... WebDec 8, 2024 · This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as …
WebSymbol Description Category UniProt ID GIFtS GC id Score; 1: GLI1: GLI Family Zinc Finger 1: Protein Coding: P08151: 56: GC12P057903: 73.14: 2: GLI2: GLI Family Zinc Finger 2
WebDetects human and mouse GLI-1. Source Polyclonal Goat IgG Purification Antigen Affinity-purified Immunogen E. coli -derived recombinant mouse GLI-1 Met1-Glu237 Accession # P47806 Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. tentukan persamaan garis singgung lingkaranWebprobed with gli zinc finger or gli non-zinc finger probes. Results with the two probes were identical. It was not surprising that the 332 bp zinc finger region probe, a probe for the region of the gli gene family with the highest degree of similarity between family members, demonstrated specificity for in situ hybridization. It tentukan persamaan garis singgung kurvaWebMay 2, 2024 · The zinc fingers contain sequence elements that place the GLI gene product among the Kruppel (Kr) family of zinc finger proteins (see 165230). (The German word 'Kruppel' means 'cripple' or 'dwarf.') The Drosophila gene is a member of the gap class of segmentation genes; thoracic and anterior abdominal segments fail to form in Kr mutant … tentukan penyelesaian persamaan 2x2 - 6x - 20 = 0 dengan memfaktorkanWebMay 2, 2024 · The zinc fingers contain sequence elements that place the GLI gene product among the Kruppel (Kr) family of zinc finger proteins (see 165230). (The German word … tentukan persamaan normal bidang rata vWebFeb 27, 2024 · GLI-1 (GLI family zinc finger 1), also known as Glioma-associated oncogene or oncogene GLI, is a 1,106 amino acid protein that localizes to both the … tentukan ph campuran 100 ml larutan ch3coohWebDec 4, 2024 · Summary. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal … tentukan persamaan garis yang melalui 2 titikWebSep 24, 1993 · Abstract. Zinc finger proteins, of the type first discovered in transcription factor IIIA (TFIIIA), are one of the largest and most important families of DNA-binding proteins. The crystal structure of a complex containing the five Zn fingers from the human GLI oncogene and a high-affinity DNA binding site has been determined at 2.6 Å resolution. tentukan persamaan garis yang melalui titik