Impact of mirna in atherosclerosis

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August undefined, 2024

Witryna1 wrz 2024 · Europe PMC is an archive of life sciences journal literature. Witryna24 mar 2024 · Atherosclerosis (AS) is a chronic arterial disorder and a significant determinant of vascular death [].Fatty streaks in arterial walls regularly develop into characteristic plaques and atheroma [].The acute rupture of these atheromatous plaques leads to local thrombosis, causing partial or total occlusion of the affected artery [].AS …

Recent advances in targeted delivery of non-coding RNA-based ...

WitrynaThis review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory response, insulin signaling and glucose/energy … WitrynaNational Center for Biotechnology Information small upright file cabinet

MicroRNA-296: a promising target in the pathogenesis of …

WitrynaAtherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the … WitrynaHere, we aimed to screen the atherosclerosis-associated miRNAs and preliminarily investigate the potential regulatory mechanism of... Endothelial Cells, Atherosclerosis and Mesenchymal Cells ... Witryna5 paź 2024 · A novel polymer that can target vascular cell adhesion molecule-1 protein (β-amino ester) NP specifically delivers anti-microRNA-712 (anti-miR-712) to inflammatory endothelial cells and reduces the high expression of pro-atherosclerotic miR-712, thus protecting from atherosclerosis. 114 Nguyen et al. developed … hijrah cinta streaming

Site‐Specific MicroRNA‐33 Antagonism by pH ... - Semantic Scholar

Frontiers Epigenetic Regulation in Pathology of Atherosclerosis: …

WitrynaMaintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and vascular inflammation. Endothelial dysfunction is encompassed … Witryna21 kwi 2024 · MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance … hijra meaning sexualityWitrynaInhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques … small upright freezer wire shelves

"Witryna20 mar 2013 · MicroRNAs (miRNAs) are small, ~22 nucleotide (nt) sequences of RNA that regulate gene expression at posttranscriptional level. These endogenous gene expression inhibitors were primarily described in cancer but recent exciting findings have also demonstrated a key role in cardiovascular diseases (CVDs), including … " - Impact of mirna in atherosclerosis

Impact of mirna in atherosclerosis

Frontiers The Potential of Exosomal RNAs in Atherosclerosis Diagnosis ...

Witryna22 sie 2024 · Impact of miRNA in Atherosclerosis. miRNAs have received most of the attention during the last decades in particular for their role in tempering gene … Witryna22 sie 2024 · MicroRNA regulation of atherosclerosis. Circ Res. 2016; 118:703–720. doi: 10.1161/CIRCRESAHA.115.306300 Link Google Scholar; 118. Eken SM, Jin H, Chernogubova E et al.. MicroRNA-210 enhances fibrous cap stability in advanced atherosclerotic lesions. Circ Res. 2024; 120:633–644. doi: …

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Witryna24 cze 2024 · The inhibition of miR-33 using pHLIP-directed macrophage targeting improves atherosclerosis regression by increasing collagen content and decreased … Witryna26 mar 2024 · Atherosclerosis has been recognized as an inflammatory disease involving the vascular wall. MicroRNAs are a group of small noncoding RNAs to …

WitrynaAtherosclerosis and lipid biology. Adenylate cyclase type 9 antagonizes cAMP accumulation and regulates endothelial signalling involved in atheroprotection. ... Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure. Coraline Heron, Anais Dumesnil, Mahmoud Houssari, ... Witryna9 maj 2024 · microRNAs (miRNAs) are implicated in the development of a wide range of diseases, including atherosclerosis, obesity, and diabetes (5–8).Among these miRNAs, aberrant let-7 expression is associated with diseases including liver and lung fibrosis and cancer (9,10).In the context of diabetes-associated atherosclerosis (DAA), previous …

Witryna20 mar 2024 · Background: Atherosclerosis (AS) is a major risk factor for cardiovascular disease. microRNAs play a key role in gene regulation in the formation and … Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. The Journal of clinical …

Witryna13 maj 2024 · In addition, the effect of miR-100-5p on the SMAD7 expression was only evident upon combined treatment in HASMCs. Interestingly, the effect of miR-100-5p …

hijra south asiaWitryna29 lis 2024 · MiR-155 is an important microRNA that modulates inflammation in atherosclerosis, but the role of miR-155 in the regulation of the NLRP3 inflammasome is still unknown. ... Corbalan-Campos J, et al. Regulation of Csf1r and Bcl6 in macrophages mediates the stage-specific effects of microRNA-155 on … small upright freezers at costcoWitrynaThe let-7 miRNA family plays a key role in modulating inflammatory responses. Vascular smooth muscle cell (SMC) proliferation and endothelial cell (EC) dysfunction are critical in the pathogenesis of atherosclerosis, including in the setting of diabetes. Here we report that let-7 levels are decrease … small upright freezer stainlessWitryna18 gru 2013 · By using a technology called "locked nucleic acids," Jo and his colleagues tested the effects of blocking miR-712 in the body. When given to mice in the rapid atherosclerosis model, the anti-miR-712 drug inhibited the development of arterial blockages. Without the drug, plaques blocked an average of 80 percent of the … small upright freezer at amazonWitryna14 lis 2024 · MiR-495 had an effect on endothelial cell proliferation and migration pathways by repressing CCL2 expression (Hartmann et al. 2015) and miR-495 inhibition could decrease accelerated atherosclerosis and increase plaque stability, contributing to the prevention of restenosis (Welten et al. 2024). hijrah fest 2021Witryna19 lut 2016 · Over the past decade, microRNAs (miRNAs) have emerged as evolutionarily conserved, noncoding small RNAs that serve as important regulators … small upright freezers at lowe\\u0027sWitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a role in endothelial function and atherosclerosis. Choline, betaine, and L-carnitine, found in animal foods, are metabolized into trimethylamine (TMA) by the gut … hijrahwater2u.com