Web7 rijen · Product Information. 26469-1-AP targets Mitoferrin 1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium … Web7 aug. 2024 · Placing animals on a low-iron diet exaggerated the reduction in mitochondrial iron observed in liver-specific Mfrn1/2-knockout animals. ... The plasmids and viral vectors for the TET-regulated human mitoferrin1-GFP lentiviral system were generated and provided by the CCEH Vector Core at the Fred Hutchinson, Seattle, WA, ...
A review of nemorosone: Chemistry and biological properties
Mfrn1 is paralogous to Mitoferrin-2 (Mfrn2), a 39 kDa protein encoded by the SLC25A28 gene in humans. Mfrn1 is highly expressed in differentiating erythroid cells and in other tissues at low levels, while Mfrn2 is expressed ubiquitously in non-erythroid tissues. Meer weergeven Mitoferrin-1 (Mfrn1) is a 38 kDa protein that is encoded by the SLC25A37 gene in humans. It is a member of the Mitochondrial carrier (MC) Superfamily, however, its metal cargo makes it distinct from other … Meer weergeven The molecular details of iron trafficking for heme and Iron-sulfur cluster synthesis are still unclear, however, Mitoferrin-1 has been shown to form oligomeric complexes with the Meer weergeven The importance of Mitoferrins in heme and Fe-S cluster biosynthesis was first discovered in the anemic zebrafish mutant frascati. Studies in mice revealed that total deletion of … Meer weergeven Mitoferrin-1 has been implicated in diseases associated with defective iron homeostasis, resulting in iron or porphyrin imbalances. … Meer weergeven • Solute carrier family Meer weergeven • Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. • Suzuki Y, … Meer weergeven Web1 feb. 2011 · Mitoferrin1 is 1 of 2 homologous mitochondrial iron transporters and is required for mitochondrial iron delivery in developing erythroid cells. We show that total … major upper body muscle groups
Mitoferrin-1 is required for brain energy metabolism and hippocampus ...
Web7 aug. 2024 · Mitochondrial iron import is essential for iron-sulfur cluster formation and heme biosynthesis. Two nuclear-encoded vertebrate mitochondrial high-affinity iron importers, … Web1 jan. 2024 · Interference of key regulators of mitochondrial lipid metabolism (e.g., ASCF2 and CS), iron homeostasis (e.g., ferritin, mitoferrin1/2 and NEET proteins), glutamine … WebMitoferrin1,2 [mitochondrial inner membrane] Show undefined attributes Go to Details catalystActivities [CatalystActivity:1362410] ferrous iron transmembrane transporter … major us battles in ww2