WebDec 16, 2009 · Bladder cancer subtypes. Bladder cancers fall into two major groups with distinct pathology and clinical behaviour and different molecular profiles [13–15].Non-invasive papillary tumours and muscle-invasive tumours represent distinct groups that at least in the majority of cases, do not represent a developmental continuum [13, … WebGenetic alterations, such as RET/PTC and AGK-BRAF fusions, are frequent events in pediatric papillary thyroid carcinoma (PTC). However, their role as prognostic markers in pediatric PTC is still under investigation. In this study, we present a patient harboring three tumor foci with distinct genetic alterations (AGK-BRAF, RET/PTC3 and an absence of canonical …
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