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WebPrilosec and leg tingling and numbness. One of the side effects I got from Prilosec, among the many, was leg tingling and numbness. I told my doctor immediately and she didn’t seem to think it was a big deal. She just said keep an eye on it. Well now I’ve been off Prilosec for a week and I still have the tingling and numbness on my left leg. WebAug 11, 2012 · Yes, yes and yes! Prilosec or Omeprazole the generic for Prilosec is what I took for 12 years. My fingers became distorted, I had gout, my legs are still in some pain … high country healthcare obgyn
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