WebAll lanes : Anti-STAT2 (phospho Y690) antibody (ab53132) at 1/300 dilution Lane 1 : HeLa cell extract treated with IFN (2500U/ml, 30mins) Lane 2 : HeLa cell extract treated with IFN … WebSTAT2 Approved name signal transducer and activator of transcription 2 Locus type gene with protein product HGNC ID HGNC:11363 Symbol status Approved Previous names signal transducer and activator of transcription 2, 113kD signal transducer and activator of transcription 2, 113kDa Alias symbols STAT113 Chromosomal location 12q13.3 Gene …
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WebMar 21, 2024 · Size: 750 amino acids Molecular mass: 87335 Da Protein existence level: PE1 Quaternary structure: Isoform alpha homodimerizes upon IFN-gamma induced phosphorylation (PubMed:8605877, 28753426). Heterodimer with STAT2 upon IFN-alpha/beta induced phosphorylation (PubMed:8605877). The heterodimer STAT1:STAT2 … WebAnti-phospho-STAT2 (Tyr689) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: STAT2, MGC59816, p113, ISGF-3, STAT113, P113 UniProt Number: P52630 …
WebMar 21, 2024 · STAT2 (Signal Transducer And Activator Of Transcription 2) is a Protein Coding gene. Diseases associated with STAT2 include Pseudo-Torch Syndrome 3 and … WebSTAT2-null mice are healthy, except that they display a profound inability to mount a productive immune response to viral exposure [43]. Surprisingly, no response to VSV viral …
WebApr 12, 2024 · Lackmann and colleagues probed the molecular size distribution of several STAT proteins in detergent-free HeLa cell extracts and found that they resided in cytoplasmic high-molecular weight complexes prior to any cytokine action, except for STAT6, which fractionated according to its monomeric molecular weight, consistent with … WebIts interaction with dengue virus NS5 inhibits the phosphorylation of STAT2, and, when all viral proteins are present (polyprotein), STAT2 is targeted for degradation. The calculated molecular weight of STAT2 is 98 kDa, but phosphorylated STAT2 is about 100-113 kDa. Protocols Standard Protocols Click here to view our Standard Protocols Publications
Web[10] [11] The length of the protein is 748 amino acids, and the molecular weight is 85 941 Dalton. [12] Expression [ edit] Distribution of STAT4 is restricted to myeloid cells, thymus and testis. [5] In resting human T cells it is expressed at very low levels, but its production is amplified by PHA stimulation. [8] other words for enablersWebMar 7, 2006 · Function. Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) ( PubMed: 2153461, PubMed: 7813427, PubMed: 10049744, PubMed: 14532120, PubMed: 15337770, PubMed: 24075985, PubMed: 21854986 ). Type I interferon binding activates the JAK … rockledge senior high schoolWebThe STAT2 gene is located on chromosome 12q13.3 and consists of 24 exons, of which 23 are coding. 1 This gene is ubiquitously expressed: at least two major protein-coding … rockledge securities toyotaWebNov 24, 2024 · Immunoglobulins constitute about 20% of the protein in plasma. The immunogen or antigen reacts with a B-cell receptor (BCR) on the cell surface of B lymphocytes. A signal is produced that directs the … other words for energy sourceWebSep 25, 2024 · In terms of amino acid alignment, STAT2 is the longest and largest isotype among human STAT family members, with a molecular weight of 113 kDa consisting of 851 amino acid residues, whereas mouse ... We would like to show you a description here but the site won’t allow us. Experimental & Molecular Medicine (Exp Mol Med) ISSN 2092-6413 (online) ISSN … eJournalPress is mission critical software providing online submission, review and … Experimental & Molecular Medicine (Exp Mol Med) ISSN 2092-6413 (online) ISSN … rockledge senior high school flWebPhospho-Stat2 Antibody detects endogenous levels of human Stat2 only when phosphorylated at Tyr690. The antibody does not significantly cross-react with … other words for engagedWebMar 21, 2024 · Genomic Locations for STAT3 Gene Latest Assembly chr17:42,313,324-42,388,540 (GRCh38/hg38) Size: 75,217 bases Orientation: Minus strand Previous Assembly chr17:40,465,342-40,540,460 (GRCh37/hg19 by Entrez Gene) Size: 75,119 bases Orientation: Minus strand chr17:40,465,342-40,540,586 (GRCh37/hg19 by Ensembl) Size: 75,245 bases … rockledge shopping center