Thioredoxin-like protein

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August undefined, 2024

WebFeb 1, 2024 · The superfamily of Thioredoxin (TRX) oxidoreductases is responsible for the reversal of diverse redox-based modifications. Superfamily members include conventional TRX, glutaredoxin (GRX), protein disulphide isomerase (PDI) and nucleoredoxin (NRX) [33 ]. Especially conventional TRX and NRX enzymes have emerged as critical regulators of … WebApr 1, 2024 · However, thioredoxin acts as an active regulatory enzyme in response to excessive ROS. Here, we performed in-silico analysis, immune challenge experiments, and functional assays of seahorse thioredoxin-like protein 1 (ShTXNL1). Evolutionary identification showed that ShTXNL1 protein belongs to the thioredoxin superfamily …

Thioredoxin domain - Wikipedia

WebThioredoxin reductases (TR, TrxR) (EC 1.8.1.9) are enzymes that reduce thioredoxin (Trx). Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. In bacteria TrxR also catalyzes the reduction of glutaredoxin like proteins known as NrdH. WebAn unusual thioredoxin (Patrx2) (108 amino acids) encoded by the PA2694 gene, is identified as a new thioredoxin-like protein based on sequence homology. Thioredoxin is a ubiquitous protein, which serves as a general protein disulfide oxidoreductase. Patrx2 present an atypical active site CGHC. We report the nearly complete 1H, 13C and 15N ... sample christening invitation for baby girl

Physiological functions of thioredoxin and thioredoxin reductase

WebJul 17, 2024 · Author summary Thioredoxin (Trx) is universally conserved thiol-oxidoreductase that regulates numerous cellular pathways under thiol-based redox control in both prokaryotic and eukaryotic organisms. Despite its central importance, the mechanism of bacterial Trx recognizes its target proteins in host cellular signaling remains unknown. … WebMar 20, 2012 · A search of the protein databases using the Basic Local Alignment Search Tool network service (National Center for Biotechnology Information, USA) indicated that the encoded protein had 44.7 to 80.4% similarity with a number of GPXs in the thioredoxin-like family (Table 2). WebApr 26, 2004 · Thioredoxin-like protein 4A. Alternative names. DIM1 protein homolog 2 publications. Spliceosomal U5 snRNP-specific 15 kDa protein 1 publication. Thioredoxin … sample christening invitation for baby boy

Overexpression of thioredoxin in transgenic mice attenuates focal ...

WebJan 17, 2002 · The 2.0 angstrom AhpD crystal structure reveals a thioredoxin-like active site that is responsive to lipoamide. We propose that Lpd, SucB (the only lipoyl protein detected in Mtb), AhpD, and AhpC together constitute a nicotinamide adenine dinucleotide (reduced)–dependent peroxidase and peroxynitrite reductase. WebMar 8, 2024 · The thioredoxin (TRX)-like superfamily is a large, diverse group of proteins containing a TRX fold. Many members contain a classic TRX domain with a redox active … sample christian christmas letterWebThioredoxin serves as a general protein disulfide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol. TR-S 2 ... sample christian statement of faith

"WebApr 7, 2009 · We found that Arabidopsis AtTDX, a heat-stable and plant-specific thioredoxin (Trx)-like protein, exhibits multiple functions, acting as a disulfide reductase, foldase chaperone, and holdase chaperone. The activity of AtTDX, which contains 3 tetratricopeptide repeat (TPR) domains and a Trx motif, depends on its oligomeric status. " - Thioredoxin-like protein

Thioredoxin-like protein

Thioredoxin - an overview ScienceDirect Topics

WebOct 10, 2014 · Thioredoxin (Trx) is a small 12-kDa redox protein that catalyzes the reduction of disulfide bonds in proteins from different biological systems. A recent study of the crystal structure of white leg shrimp thioredoxin 1 from Litopenaeus vannamei (LvTrx) revealed a dimeric form of the protein mediated by a covalent link through a disulfide bond between … WebNov 1, 2001 · HCF164 encodes a thioredoxin-like protein that possesses disulfide reductase activity. The protein was found in the chloroplast, where it is anchored to the thylakoid membrane at its lumenal side. HCF164 is closely related to the thioredoxin-like protein TxlA of Synechocystis sp PCC6803, most probably reflecting its evolutionary origin.

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WebFeb 5, 2024 · Txnl1 is the first example of a direct connection between protein reduction and proteolysis, two major intracellular protein quality control mechanisms. Title: Thioredoxin … WebApr 22, 2014 · A further reduced sequence identity with EcTrx (16%) characterizes the as yet unannotated thioredoxin-like sequence from P. furiosus, which also diverges from canonical thioredoxins at the level ...

WebMar 21, 2024 · TXN (Thioredoxin) is a Protein Coding gene. Diseases associated with TXN include Retinal Ischemia and Myocarditis . Among its related pathways are … WebJul 27, 2024 · Functional enrichment analysis indicated that these S-glutathionylated proteins were involved in diverse important biological processes, such as pyruvate metabolism and glycolysis. Furthermore, we studied a thioredoxin-like protein (Tlp) to explore the effect of S-glutathionylation on interspecies competition between oral …

WebAug 17, 2009 · An example is the thioredoxin-like protein A (TlpA) of the nitrogen-fixing soil bacterium Bradyrhizobium japonicum. Mutational analysis indicates that this protein is essential for the biogenesis and maturation of cytochrome oxidase of the aa 3 type . Although bioinformatics analysis of bacterial genomes identifies proteins related to CcmG … WebJul 27, 2024 · Functional enrichment analysis indicated that these S-glutathionylated proteins were involved in diverse important biological processes, such as pyruvate …

WebThe thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thioredoxin, is a key antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance. The Trx system provides the electrons to thiol-dependent peroxidases (peroxiredoxins) to ...

WebApr 14, 2024 · SynDLP, the dynamin-like protein of the cyanobacterium Synechocystis sp. PCC 6803, forms ordered oligomers in solution. ... formation of disulfide bridges is … sample christening invitation wordingWebDec 14, 2024 · thioredoxin; thioredoxin-like protein; 2-Cys peroxiredoxin; Acknowledgments. We thank the Biomaterial Analysis Center at the Tokyo Institute of Technology for … sample christian wedding ceremony outlineWebApr 1, 2024 · However, thioredoxin acts as an active regulatory enzyme in response to excessive ROS. Here, we performed in-silico analysis, immune challenge experiments, and … sample christian wedding invitation wordingWebApr 15, 2024 · We then used a combination of ELISA-based assay and purification strategies to show that deCoAlation is an enzyme-driven mechanism. Using mass-spectrometry and … sample christian welcome greetings speechesWebJan 17, 2002 · The 2.0 angstrom AhpD crystal structure reveals a thioredoxin-like active site that is responsive to lipoamide. We propose that Lpd, SucB (the only lipoyl protein … sample christian wedding programsWebThioredoxins are ubiquitous antioxidant enzymes that play important roles in many health-related cellular processes. As such, the fundamental knowledge of how these enzymes … sample christingle serviceWebThioredoxin Interacting Protein. Thioredoxin-interacting protein (TXNIP), also known as thioredoxin-binding protein 2 (TBP-2)/vitamin D3up-regulated protein 1 (VDUP1), is an α … sample christmas appeal letters